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MiniPCR Wrongfully Convicted Activity - Worksheet

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5. Imagine that your DNA evidence was exposed to the elements for an extended time. Because the DNA is degraded, you only get results for the first two STR locations in the table above (D2S441 and D5S818). a. What would the random match probability be then? Show your work. Type your answer here. b. The current US population is 331,000,000 (331 million). How many individuals in the US are predicted to match your evidence DNA profile? Show your work. Type your answer here. c. How confident would you be in using this DNA sample to convict someone of a crime? Type your answer here. 6. Now assume you only get results for the last 2 STR locations in the table above (D16S539 and D18S51) a. What would the random match probability be then? Show your work. Type your answer here. b. The current US population is 331,000,000 (331 million). How many individuals in the US are predicted to match your evidence DNA profile? Show your work. Type your answer here. c. How confident would you be in using this DNA sample to convict someone of a crime? Type your answer here. 7. Explain why the random match probabilities in questions 5 and 6 are so different even though they were both calculated using two STR locations. Type your answer here. Electrophoresis Forensics Lab: Wrongfully Convicted? Student E-worksheet™. Release: September 2023. © 2023 by miniPCR bio TM

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