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MiniPCR Wrongfully Convicted Activity - Student Guide

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miniPCR bio™ Electrophoresis Forensics Lab. Wrongfully Convicted? Instructor's and Student's Guide Version: 1.1 - Release February 2022 - © 2022 by miniPCR bio™ Additional Supports P./32 6. Now assume you only get results for the last 2 STR locations in the table above (D16S539 and D18S51) A. What would the random match probability be then? Show your work. B. The current US population is 331,000,000 (331 million). How many individuals in the US are predicted to match your evidence DNA profile? Show your work. C. How confident would you be in using this DNA sample to convict someone of a crime? 7. Explain why the random match probabilities in questions 5 and 6 are so different even though they were both calculated using two STR locations. 8. Brainstorm at least one example where you think two people are more likely to have a similar STR profile than two randomly selected individuals. Explain your reasoning.

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