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MiniPCR Wrongfully Convicted Activity - Instructor Guide

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miniPCR bio™ Electrophoresis Forensics Lab. Wrongfully Convicted? Instructor's and Student's Guide Version: 1.1 - Release February 2022 - © 2022 by miniPCR bio™ Additional Supports P./31 C. How confident would you be in using this DNA sample to convict someone of a crime? 5. Imagine that your DNA evidence was exposed to the elements for an extended time. Because the DNA is degraded, you only get results for the first two STR locations in the table above (D2S441 and D5S818). A. What would the random match probability be then? Show your work. B. The current US population is 331,000,000 (331 million). How many individuals in the US are predicted to match your evidence DNA profile? Show your work. C. How confident would you be in using this DNA sample to convict someone of a crime? Scientific notation In fraction form In words 1E-6 1/1,000,000 one in a million 1E-9 1/1,000,000,000 one in a billion 1E-12 1/1,000,000,000,000 one in a trillion Table 3. Interpreting scientific notation B. Scientific notation is often used with very small numbers. Compare the random match probability that you just calculated with the scientific notation to the right. What order of magnitude is the random match probability? i. On the order of one in a million ii. On the order of one in a billion iii. On the order of one in a trillion

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